Molecular machines are nanoscale macromolecular complexes performing specific functions for an organism. Cells build thousands of such custom-designed complexes including the ribosome, transcriptional machinery, motors and transporters, all of which work in a precisely organized manner. Knowledge of their properties is of crucial importance in bionanotechnology.

Joanna Trylska and her group explore the function, dynamics, and physical properties of macromolecular assemblies to understand their activities in the cell. The main object of our studies is the ribosome - the ribonucleoprotein complex responsible for protein synthesis. The ultimate goal is to search for antibiotic analogs inhibiting the function of bacterial ribosomes.

New! MISDoMP project - PhD fellowship 

Centre of New Technologies University of Warsaw Żwirki i Wigury 93 02-089 Warsaw, Poland tel. +48 (22) 5540-843 fax +48 (22) 5540-801 bionano@icm.edu.pl

Funding

• ICM, University of Warsaw
• Polish Ministry of Science and Higher Education
• Fogarty International Center, National Institutes of Health
• Foundation for Polish Science
• European Union, European Regional Development Fund

Biomolecular Machines Laboratory logo by Krzysztof Rychter